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Francis Crick Quotes


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Quotes by Francis Crick

Showing 11-20 of 22 Quotes by Francis Crick

It is one of the more striking generalizations of biochemistry - which surprisingly is hardly ever mentioned in the biochemical textbooks - that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.

~Francis Crick

Topics: Amino Bases Biochemistry Ever Four Generalizations Hardly Mentioned Minor More Nature Reservations Same Striking Surprisingly Textbooks Throughout Twenty Which

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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.

~Francis Crick

Topics: Code Direct Earlier Evidence Genetic Indeed Indirect Mentioned Methods Opposed Shown

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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.

~Francis Crick

Topics: Addition Correct Example For Example Grouping Incorrect Message Obtain Place Reading Readings Right Right Place Sets Shall Start Then Three Triplets Two Which

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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.

~Francis Crick

Topics: Any Attempt Bad Both Code Consider Does Evidence Foundation Good Good And Bad Indeed Legitimate Logical Some Then

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If poly A is added to poly U, to form a double or triple helix, the combination is inactive.

~Francis Crick

Topics: Added Combination Double Form Triple

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The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.

~Francis Crick

Topics: Acid Ambiguous Amino Certainly Code Expect However May Meaning Meaning Of Minority More Observation Possibility Raises Than Triplets Unfortunate Which Would

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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.

~Francis Crick

Topics: Acid Backbone Base Bases Divided Group How Nothing Perfectly Regular Sequence Show Us Which

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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the - class as having one too few.

~Francis Crick

Topics: Base Class Extra Few Genetic Having Message Other Point Simplicity Some Think Too

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Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap.

~Francis Crick

Topics: Along Base Certain Fairly Find Genetic In Other Words Member Message More Now Other Overlap Read Seems Two Which Words

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Attempts have been made from a study of the changes produced by mutation to obtain the relative order of the bases within various triplets, but my own view is that these are premature until there is more extensive and more reliable data on the composition of the triplets.

~Francis Crick

Topics: Attempts Bases Been Changes Composition Data Extensive Made More Mutation My Own Obtain Order Own Premature Produced Relative Reliable Study Triplets Until Various View Within

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Biography

Nationality: English

Type: Scientist

Born: June 8th, 1916

Died: July 28th, 2004

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